Maternal suicide is a leading cause of maternal mortality. Despite common misconceptions, pregnancy and the postpartum period do not protect against the risk of psychiatric disorders or suicide. It has become increasingly urgent and important to normalize the discussion of maternal suicide to raise awareness and double-down on maternal suicide tracking and prevention efforts. In… Read More »
Essential Reads: Investigational Treatment of Depressive Disorders With Neuroactive Steroids: Potential Implications for PMDD Neuroactive steroids or neurosteroids are a new class of medications which appear to have anxiolytic and antidepressant effects and have received a great deal of attention over the past few years. Most of neuroactive steroids currently under investigation as antidepressants are derivatives… Read More »
Essential Reads: Neurosteroids, Allopregnanolone and Vulnerability to Depression in Women Women are twice as likely as men to suffer from a depressive disorder. In addition, they are vulnerable to mood disorders associated with reproductive functioning, specifically premenstrual dysphoric disorder, perinatal depression, and perimenopausal depression. There is strong evidence to indicate that biological factors (genetic vulnerability,… Read More »
Essential Reads: ADHD in Girls and Women In childhood, ADHD is clearly more common in boys than in girls; however, in adult samples, the sex differences in prevalence are mush smaller. There is also increasing recognition that girls and women may present with a different constellation of symptoms and behaviors. For example, in children, girls… Read More »
Over the last 20 years, we have accumulated data to support the use of many different antidepressants during pregnancy, including serotonin reuptake inhibitors and the tricyclic antidepressants. In this post, we review the most recent data on the reproductive safety of and bupropion (Wellbutrin), summarized in two recent reviews from Hendrick and colleagues (2017) and… Read More »